Partnering with exercise, NMN supplements effectively enhance exercise performance and endurance in middle-aged athletes by bolstering aerobic capacity. Amidst a global quest among athletes to elevate their endurance and performance, significant research strides have been made. Recent studies in rodents have underscored the efficacy of nicotinamide mononucleotide (NMN) supplementation in enhancing exercise endurance. However, the question remains: do these NMN-related benefits extend to humans?
To address this, Hu. from Guangzhou Sports University conducted a human study, published in the Journal of the International Society of Sports and Nutrition. Their research revealed that oral NMN intake notably elevates aerobic capacity, measured by the muscles’ oxygen consumption, in adult runners. Furthermore, this NMN supplementation enhances skeletal muscle’s ability to utilize oxygen for heightened energy production during endurance exercise. Let’s delve into the intricacies of the study.
Over the last decade, research conducted on animals has revealed the beneficial impact of NMN supplements on rodents, particularly in terms of exercise capacity, healthy aging, and increased longevity. For instance, NMN supplementation enhances energy production, resulting in a remarkable 50% improvement in physical endurance. Moreover, it aids in various physiological aspects, such as insulin sensitivity and neuron functions.
Furthermore, certain studies have indicated that NMN supplements can enhance insulin sensitivity and improve muscle function in pre-diabetic women and men aged 60 years.
Pairing NMN supplementation with training enhances exercise endurance.
To explore whether middle-aged, healthy athletes can also experience similar benefits from NMN, Hu et al. supplemented runners with 300, 600, or 1200 mg of NMN for a duration of 6 weeks. During this period, these three dosage groups underwent training sessions 5 to 6 times per week, lasting 40 to 60 minutes each, followed by pulmonary and cardiac exercise tests.
The results from endurance training assessments revealed that NMN supplements significantly enhance the body’s capacity to absorb and deliver oxygen to body tissues at doses of 600 and 1200 mg/day.
Hu and colleagues further examined the safety of high doses of NMN supplements for runners. Remarkably, none of the runners exhibited side effects such as abnormal heart rate, indicating that this supplement is safe and well-tolerated at a dosage of 1200 mg/day.
In conclusion,
the study results indicate that NMN supplements effectively enhance oxygen consumption capacity in middle-aged athletes, thereby improving their exercise performance and endurance.