NMN takes care of your skin from UV damage
The scorching sun hides ultraviolet rays that harm our skin. When the sun shines directly on our skin, we are easily sunburned and even cause skin aging.
Prolonged exposure to ultraviolet rays can cause skin sunburn, redness, swelling, and pain. What’s more serious is that ultraviolet rays can also destroy the collagen and elastic fibers of the skin, causing the skin to lose its elasticity, accelerating skin aging, and accelerating aging.
So how to fight aging?
First, use parasols, wide-brimmed hats and other items to block the sun and block ultraviolet rays.
Secondly, pay attention to the balance and nutrition of the diet, and supplement with appropriate amounts of vitamins and antioxidants.
Thirdly, strengthen your physique through exercise and improve your body’s anti-aging ability.
Well enough? Taking NMN nutritional supplements can repair cells damaged by ultraviolet rays, help the skin resist oxidation, and delay the aging process of the skin.
Experimental proof
Protection of skin cells from UV damage depends on NMN synthesis.
Our cells rely on nicotinamide adenine dinucleotide (NAD+) for function and survival. Aging-induced declines in NAD+ levels have been linked to metabolic disorders, cancer, and neurodegenerative diseases, among other diseases. Similar to aging, harmful UV rays from the sun also deplete NAD+ .
Tsuji Naito and colleagues from Japan’s DHC Corporation Laboratory published a study in the Journal of Photochemistry and Photobiology showing that UV damage can initiate NAD+ synthesis and NAD+ consumption enzymes, a balancing act that determines the appearance of human skin. Cell survival or dysfunction.
They also pointed out that UV radiation can activate nicotinamide phosphoribosyltransferase (NAMPT), which produces the NAD+ precursor nicotinamide mononucleotide (NMN), and can also activate the NAD+ consuming enzyme polyADP-ribose polymerase (PARP). .
PARP
(poly ADP-ribose polymerase) is a DNA repair enzyme. And when DNA damage occurs, PARP is activated and uses NAD+ to assist in repairing the damage. The activity of PARP consumes the available NAD+ in the cell, thereby reducing the total amount of NAD+.
If the amount of NAD+ synthesized is reduced, this balance will be disrupted, and PARP will continue to severely deplete NAD+ levels, causing skin cell proliferation stagnation and dysfunction.
Therefore, supplementing NMN (100µM), the precursor of NAD+, or nicotinamide ribose (NR; 50µM) can maintain this balance, thereby enhancing the recovery ability of cells and promoting the health of skin cells during the aging process.
Tsuji Naito also said: “Our findings not only provide a decisive explanation for NAMPT’s involvement in skin protection from daily UVA/B exposure, but also identify NMN and NR , which can be used in age-related skin diseases and functional decline, As potential therapeutic agents and preventive options. “
NMN18000 adds resveratrol, CoQ10, and a patented formula of 5-ALA.
5-ALA (5-aminoacetate phosphate) is a naturally occurring amino acid essential for life. This substance is produced in the cells of all living things, and when it combines with iron in the body, it becomes “heme.” The production of 5-ALA in the body peaks in infancy and declines with age.
Ingesting 5-ALA can promote cell metabolism, rejuvenate the body, and enhance the ability to burn sugar and convert it into energy, thereby improving skin condition and making the skin shiny and translucent.